Job Description We seek a Scientist / Senior Scientist within the Biology Group in the Department of Research & Operation at our US site, Redwood Shores, California. In this role, you will be responsible for developing and executing assays that support screening, mechanism of action, translational relevance, and/or biomarker identification for several programs focused on targeting myeloid cells for cancer immunotherapy. Job Duties: * Execute standard immunological assays (cell proliferation, cytokine analysis, phenotyping) using a variety of methods (plate-based assays, ELISA, flow cytometry, cell reporter assays) * Creatively adapt standard assays or develop novel assays to test the unique biology of our platform. * Isolate and analyze cell subsets of interest from various tissues or mixed cell suspensions. * Support PK/PD and biomarker analysis as needed * Present data at regular group meetings and recommend next steps * Document research activities and findings in electronic laboratory notebooks and reagent registries in keeping with the highest industry standards * Exhibit excellent analytical, organizational, communication, and time management skills * Lab activities will be ~75% time Required Experience/Qualifications * BA/BS or equivalent in biology, immunology, or a related discipline with 4+ years of relevant industry or academic research experience; MS degree or equivalent in biology, immunology, or a related discipline and 2+ years of experience conducting original research * Deep understanding of immunology. * Experience developing immune assays and working with primary immune cells (B, T, myeloid, and NK) is required. * Proficiency in developing multi-parameter flow cytometry panels, analysis of immune cell function, and immune cell isolation. * Skilled in the development of assays such as binding, internalization, and/or various immunoassays to assess complex biology * Excellent communication and interpersonal skills, enthusiasm and curiosity in science, and the ability to thrive in a dynamic cross-functional environment * Experience with drug discovery and/or early development * Experience with bioinformatics/computational biology tools would be a plus Skills • Excellent laboratory skills • Excellent data analysis and organizational skills • Excellent communication skills • Ability to work independently and as part of a team hiring manager: [email protected]
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